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KMID : 0384320000210010028
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Korean Journal of Family Medicine
2000 Volume.21 No. 1 p.28 ~ p.37
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Dyspeptic Symptom Severity Related to Helicobacter pylori and Stress in Functional Dyspepsia
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Kim Cheol-Hwan
Shin Ho-Chul
Park Yong-Woo
Lee Haeng
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Abstract
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Background : It is well-known that dyspeptic symptoms in functional dyspepsia are related to psychological factors such as stress and mood disorder. But it is still controversial whether H. pylori infection is a important factor for functional dyspepsia. We conducted this study to investigate whether H. pylori infection or stress are related to dyspeptic symptom severity in functional dyspepsia.
Methods : From Mar. 1 1999 to Apr. 30 1999, attendees to a Health Screening Center and a Family Practice Center were eligible study subjects. The subjects were responded to questionnaire including dyspeptic symptom severity items and BEPSI-K(stress scale). And among eligible subjects, one hundred and thirty two diagnosed with functional dyspepsia by gastrofibroscopy were final study subjects. H. pylori infection was confirmed by antral biopsies & smear (Giemsa stain).
Results : In functional dyspepsia, high BEPSI-K score group(upper tertile) complained more severe dyspeptic symptom severity than low BEPSI-K score group(lower tertile) after adjusted for other variables(adjusted OR=8.389, 95% C.I.=2.232-31.231). But the dyspeptic symptom severity was not associated with H. pylori infection status (adjusted
OR=1.514, 95% C.I.=0.567-4.046).
Conclusions : The dyspeptic symptom severity in functional dyspepsia was associated with stress but not with H. pylori infection status.
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KEYWORD
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Functional dyspepsia, Helicobacter pylori, Stress
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